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Search Results for " cell cycle arrest "

304

抑制剂 & 化合物

64

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T11960	MBM-55	GSK-3; MAPK; DYRK; Akt; Chk; Bcr-Abl; CDK; S6 Kinase; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
	MBM-55 是一种有效的中心体相关激酶 2 (NEK2) 抑制剂，IC50 为 1 nM。 MBM-55 通过诱导细胞周期停滞和凋亡有效抑制癌细胞的增殖。
T14066	9-ING-41	Apoptosis; GSK-3; Autophagy	Apoptosis; Autophagy; PI3K/Akt/mTOR signaling; Stem Cells
	9-ING-41 是基于马来酰亚胺的 ATP 竞争性和选择性的糖原合酶激酶-3β 抑制剂，IC50为 0.71 μM。它显著导致癌细胞的细胞周期停滞，自噬和凋亡，具有增强化疗药物抗肿瘤作用的潜力，有抗癌活性。
T23133	Pentamidine	Phosphatase; Antibacterial; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology
	Pentamidine 是抗微生物剂，会干扰 DNA 的生物合成。它是选择性蛋白酪氨酸磷酸酶和再生肝磷酸酶抑制剂。它可用于冈比亚锥虫病，抗锑利什曼病和卡氏肺孢子虫肺炎的研究，有抗肿瘤活性，抗菌活性。
T6207	SC144	Apoptosis; Interleukin	Apoptosis; Immunology/Inflammation
	SC144 是一种口服活性 gp130 抑制剂。它结合 gp130，诱导 gp130 磷酸化(S782) 和去糖基化，消除 Stat3 磷酸化和核易位，进一步抑制下游靶基因的表达。它对 gp130 配体触发的信号转导有明显的抑制作用，可诱导人卵巢癌细胞凋亡。
T22461	YKL-5-124	CDK	Cell Cycle/Checkpoint
	YKL-5-124 是选择性不可逆CDK7共价抑制剂，对CDK7和CDK7/Mat1/CycH 的IC50分别为 53.5 nM 和 9.7 nM。它诱导强烈的细胞周期停滞，并抑制 E2F 驱动的基因表达。它对 CDK7 的生化和细胞选择性优于 CDK12/13。它对CDK7的选择性比 CDK9 和 CDK2 高 100 倍以上。
T15012	Crolibulin EPC2407	Microtubule Associated	Cytoskeletal Signaling
	Crolibulin (EPC2407) 是一种微管蛋白聚合抑制剂，具有诱导凋亡和抑制细胞生长的作用。它有抗肿瘤活性，还具有心血管毒性和神经毒性。
T36816	S-trityl-L-Cysteine STLC	Kinesin	Cytoskeletal Signaling
	S-Trityl-L-cysteine 是别构驱动蛋白Eg5的选择性抑制剂。rityl-L-cysteine 抑制基础 ATPase 活性的IC50为 1 μM，抑制微管激活的 ATPase 活性的IC50为 140 nM。S-Trityl-L-cysteine 显示出抗肿瘤活性。
T10460	Batabulin 巴他布林,T138067	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Batabulin (T138067) 是一种抗肿瘤剂，可与 β-微管蛋白同种型的子集共价且选择性地结合，从而破坏微管聚合。它影响细胞形态并导致细胞周期停滞，最终诱导细胞凋亡。
T1654	Pentamidine isethionate Pentamidine isethionate salt,Pentamidine diisethionate,喷他脒羟乙磺酸盐	Phosphatase; Antibacterial; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology
	Pentamidine isethionate (Pentamidine diisethionate) 是抗微生物剂，会干扰 DNA 的生物合成。它抑制寄生虫Leishmania infantum，IC50为 2.5 μM。它是选择性蛋白酪氨酸磷酸酶和再生肝磷酸酶抑制剂。它有抗肿瘤和抗菌活性。
T2641	KRCA-0008 KRCA 0008,KRCA0008	ACK; ALK	Angiogenesis; Tyrosine Kinase/Adaptors
	KRCA-0008 是高效的、选择性的 ALK/Ack1 抑制剂，对ALK 和Ack1的IC50值分别为12nM 和4nM，显示出非hERG 依赖性药物活性。
T4215	TCS-PIM-1-4a 5-[[3-(三氟甲基)苯基]亚甲基]-2,4-噻唑烷二酮,SMI-4a	Apoptosis; Pim	Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling
	TCS-PIM-1-4a (SMI-4a) 是一种泛-Pim 激酶抑制剂，可通过激活 AMPK 来阻断 mTORC1的活性。它可杀死多种髓样和淋巴样细胞系，IC50值为 0.8 μM 至 40 μM。
T4134	OTS514 hydrochloride OTS-514 hydrochloride,OTS514 hydrochloride(1338540-63-8(free base))	Apoptosis; TOPK	Apoptosis; MAPK
	OTS514 hydrochloride 是一种高效的TOPK 抑制剂，IC50为 2.6 nM。它可强效抑制 TOPK 阳性的肿瘤细胞生长，诱导细胞周期停滞和凋亡。
T23132	Pentamidine dihydrochloride 喷他脒二盐酸盐,MP-601205 dihydrochloride	Phosphatase; Antibacterial; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology
	Pentamidine dihydrochloride (MP-601205 dihydrochloride) 是一种抗微生物剂，会干扰 DNA 的生物合成。它是选择性蛋白酪氨酸磷酸酶和再生肝磷酸酶抑制剂。它可用于冈比亚锥虫病，抗锑利什曼病和卡氏肺孢子虫肺炎的研究，有抗肿瘤活性，抗菌活性。
T2241	Alisertib MLN 8237,4-[[9-氯-7-(2-氟-6-甲氧基苯基)-5H-嘧啶并[5,4-D][2]苯并氮杂卓-2-基]氨基]-2-甲氧基苯甲酸	Apoptosis; Aurora Kinase; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Alisertib (MLN 8237) 是一种口服活性和选择性的Aurora A 激酶抑制剂，IC50值为 1.2 nM。它通过靶向白血病细胞中的AKT/mTOR/AMPK/p38途径诱导其凋亡和自噬，具有抗肿瘤活性。
T6303L	CCT128930 hydrochloride CCT128930 hydrochloride(885499-61-6 Free base)	Apoptosis; Akt; PKA; mTOR; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	CCT128930 hydrochloride (CCT128930 hydrochloride) 是一种选择性 AKT 抑制剂，具有抗肿瘤活性。它通过靶向 AKT 的 Met282 (PKA-AKT 嵌合体的 Met173)，对 PKA 激酶具有 28 倍的选择性，对 p70S6K 具有 20 倍的选择性。
T2170	SKF-96365 hydrochloride 1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑,SKF96365	Apoptosis; Potassium Channel; Calcium Channel; TRP/TRPV Channel; Autophagy	Apoptosis; Autophagy; Membrane transporter/Ion channel; Metabolism
	SKF-96365 hydrochloride (SKF96365) 是store-operated Ca2+entry 抑制剂，也是TRP channel 阻滞剂。它显著抑制豚鼠离体心脏 hERG、hKCNQ1/hKCNE1、hKir2.1 和 hKv4.3 电流，延长QTc 间期。它通过诱导结直肠癌细胞的细胞周期阻滞和凋亡起抗肿瘤作用。
T6303	CCT128930	Akt; PKA; S6 Kinase; Autophagy	Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	CCT128930 是一种 ATP 竞争性，选择性 AKT 抑制剂。它通过靶向 AKT 的 Met282 (PKA-AKT 嵌合体的 Met173)，对 PKA 激酶具有 28 倍的选择性，对 p70S6K 具有 20 倍的选择性，具有抗肿瘤活性。
T4134L	OTS514 OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514	Apoptosis; TOPK	Apoptosis; MAPK
	OTS514 (OTS514 Hydrochloride) 是一种高效的 TOPK 抑制剂，IC50为 2.6 nM。它强效抑制 TOPK 阳性的肿瘤细胞生长，还可诱导细胞周期停滞和凋亡。
T10343	AOH1160 N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	AOH1160 是增殖细胞核抗原 (PCNA) 的抑制剂。 AOH1160 通过干扰 DNA 复制导致细胞周期停滞并诱导细胞凋亡。
T9712	PF07104091 PF-07104091	CDK	Cell Cycle/Checkpoint
	PF07104091抑制CDK2，这可能导致细胞周期阻滞，诱导细胞凋亡，抑制肿瘤细胞增殖。
T2425	KPT185 KPT-185,KPT 185	CRM1	Membrane transporter/Ion channel
	KPT185 (KPT 185) 是一种选择性 CRM1 抑制剂，可诱导细胞凋亡、细胞周期停滞。
T19699	Triciribine phosphate TCN-P,VD 002,VQD-002	Apoptosis; Akt	Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Triciribine phosphate (VD 002) 是一种高选择性的 AKT 抑制剂，可诱导细胞周期停滞和半胱天冬酶依赖性细胞凋亡，抑制新生血管的生成，可用于研究白血病。
T34262	RAPTA-C	Apoptosis	Apoptosis
	RAPTA-C 可通过线粒体和 p53-JNK 途径诱导 EAC 细胞周期停滞和凋亡，可用于研究乳腺癌和卵巢癌。
T2615	Flavopiridol hydrochloride Alvocidib Hydrochloride,NSC 649890,MDL 107826A,HL 275,FLAVOPIRIDOL HCL,NSC 649890 HCl	HIV Protease; CDK; Autophagy	Autophagy; Cell Cycle/Checkpoint; Microbiology/Virology; Proteases/Proteasome
	Flavopiridol hydrochloride (MDL 107826A) 是一种CDK 的广谱抑制剂，与 ATP 竞争性地抑制 CDK1，CDK2 和 CDK4 的活性，IC50值分别为 30, 170, 100 nM。
T10268	AGX51	Others	Others
	AGX51 是 DNA 结合蛋白抑制剂 (ID) 的拮抗剂。 AGX51 治疗导致泛 Id 降解、细胞周期停滞和细胞死亡。
T17187	TZ9	Apoptosis; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	TZ9 是一种具有选择性和有效性的 Rad6 抑制剂，具有抗癌和而抗肿瘤活性。TZ9 对 Rad6B 诱导的组蛋白 H2A 泛素化有抑制作用。TZ9 诱导细胞周期停滞和细胞凋亡。
T77647	Tubulin polymerization-IN-43	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Tubulin polymerization-IN-43 是一种微管蛋白聚合 (tubulin polymerization) 抑制剂。Tubulin polymerization-IN-43 具有多种作用，通过靶向 Colchicine 位点破坏细胞微管网络，促进白血病细胞的细胞周期停滞在 G2/M 期和细胞凋亡 (apoptosis)。Tubulin polymerization-IN-43 具有抗血管生成活性。
T0975	Chlorambucil CB-1348,Chloroambucil,苯丁酸氮芥,WR-139013	DNA Alkylator/Crosslinker; DNA Alkylation	DNA Damage/DNA Repair
	Chlorambucil (CB-1348) 是一种口服活性的氮芥类双功能烷基化剂，具有抗肿瘤活性，可用于研究淋巴细胞白血病、卵巢癌和乳腺癌以及霍奇金病。
T3485	Probimane AT-2153,MM-159	Others	Others
	Probimane (AT-2153) 具有抗增殖作用、细胞周期 G2/M 期阻滞和用 MST-16 阻断人类肿瘤细胞系中的染色体分离。
T4189	4-Oxofenretinide 3-Keto fenretinide,4-氧代维甲酰酚胺	cell cycle arrest	Cell Cycle/Checkpoint
	4-Oxofenretinide (3-Keto fenretinide) 是一种最近发现的 fenretinide 代谢物，可诱导显着的 G2-M 细胞周期停滞和细胞凋亡。
T77667	PI3Kδ-IN-16	Apoptosis; PI3K	Apoptosis; PI3K/Akt/mTOR signaling
	PI3Kδ-IN-16 是一种具有选择性和有效的 PI3Kδ 抑制剂，具有抗癌抗增殖活性，诱导细胞周期停滞和细胞凋亡。
T19831	Sodium Oxamate 草氨酸钠,oxamate sodium,Oxamic acid sodium salt,Aminooxoacetic acid sodium salt,SO	Apoptosis; Dehydrogenase; CDK	Apoptosis; Cell Cycle/Checkpoint; Metabolism
	Sodium Oxamate (Oxamic acid sodium salt) 是一种 LDH 抑制剂，对 LDHA 特异性抑制。Sodium Oxamate 具有抗肿瘤活性，可以诱导细胞周期阻滞、细胞凋亡。
T36898	Sandacanol Sandranol,2-Ethyl-4-(2,2,3-trimethylcyclopent-3-en-yl)-but-2-en-1-ol	Apoptosis	Apoptosis
	Sandacanol（Sandranol）是一种选择性嗅觉受体（OR10H1）激动剂。Sandacanol可诱导膀胱癌细胞的细胞周期停止和部分凋亡，可降低细胞迁移率和增殖率。
T11718	JI051 JI-051	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	JI051 具有抗肿瘤作用，能够与癌症相关蛋白伴侣 prohibitin 2 (PHB2) 相互作用，通过抑制 Notch 下游效应基因 Hes1 转录来促使细胞周期停滞，抑制HEK293 细胞和胰腺癌细胞增殖。
T3048	10058-F4 c-Myc Inhibitor	c-Myc; Autophagy	Autophagy; Cell Cycle/Checkpoint
	10058-F4 (c-Myc Inhibitor) 是一种细胞渗透性噻唑烷酮，可特异性抑制 c-Myc-Max 相互作用并防止 c-Myc 靶基因表达的反式激活；诱导细胞周期停滞和凋亡。
T73515	MC2590	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	MC2590 是一种具有有效性和选择性的组蛋白脱乙酰酶 (HDAC) 抑制剂，抑制 HDAC1-3、-6、-8 和 -10 的活性，诱导细胞周期停滞，促进细胞凋亡。
T1844	KPT330,(E)- (E)-RN,KPT-330,KPT330,KPT 330	Others; CRM1	Membrane transporter/Ion channel; Others
	(E)-RN (KPT 330) 是一种 CRM1 选择性核输出抑制剂。它抑制细胞核中的蛋白质运输并诱导间皮瘤细胞中的细胞周期停滞和凋亡。
T22646	CFM 4 CFM-4,CFM4	Apoptosis; APC	Apoptosis; Cell Cycle/Checkpoint
	CFM 4 是一种有效的小分子 CARP-1/APC-2 拮抗剂，阻止 CARP-1 与 APC-2 结合，促使 G2M 细胞周期阻滞，引起细胞凋亡，其 IC50 范围为 10-15 μM。CFM 4 对耐药人类乳腺癌细胞的生长有抑制作用。
T24212	XX-650-23 XX65023,XX 650 23	Apoptosis; Epigenetic Reader Domain	Apoptosis; Chromatin/Epigenetic
	XX-650-23 是一种小分子 CREB 抑制剂，阻断 CREB 与其所需的共激活因子 CBP（CREB 结合蛋白）之间的关键相互作用，诱导AML细胞凋亡和细胞周期停滞，可用于研究急性髓系白血病（AML）。
T78701	Tubulin inhibitor 32	Apoptosis	Apoptosis
	Tubulin inhibitor 32是一种口服活性的新型微管抑制剂，具有抗增殖和抗肿瘤活性，可抑制微管聚合，可诱导细胞凋亡及在G2/M期引起细胞周期停滞。
T10760	Ceramides Mixture 神经酰胺混合物,神经酰胺	Telomerase	DNA Damage/DNA Repair
	Ceramides Mixture 是表皮渗透屏障的主要脂质成分，参与生长抑制，细胞周期停滞和端粒酶活性的调节。它是一种内源性神经酰胺，由含羟基和非羟基脂肪酸的神经酰胺组成。
T12040	Milademetan RAIN-32,DS-3032,DS3032b	Mdm2; Others	Apoptosis; Others
	Milademetan (DS-3032) 是一种具有口服活性和有效性的 MDM2 抑制剂，具有抗肿瘤活性，诱导 G1 细胞周期阻滞、衰老和凋亡。Milademetan 可用于研究急性髓系白血病和实体肿瘤。
T9703	GSK778	Epigenetic Reader Domain	Chromatin/Epigenetic
	GSK778 是BET 蛋白BD1溴结构域的选择性抑制剂，对BRD2 BD1、BRD3 BD1、BRD4 BD1、BRDT BD1的IC50分别为75 nM，41 nM，41 nM 和143 nM。
T67741	SU056	Others	Others
	SU056 是一种 YB-1 抑制剂，可以抑制与其相关的下游蛋白质和通路。SU056 可以诱导卵巢癌细胞周期停滞、凋亡 (apoptosis)，并抑制癌细胞迁移。SU056 可增强紫杉醇的细胞毒性。
T6970	RK33 RK-33,RK 33	COX	Immunology/Inflammation; Neuroscience
	RK33 (RK 33) 是 DDX3（一种 RNA 解旋酶）的一流小分子抑制剂，可导致 G1 细胞周期停滞，诱导细胞凋亡，并促进 DDX3 过表达细胞的辐射增敏。
T11961	MBM-55S	GSK-3; MAPK; Akt; Bcr-Abl; CDK; S6 Kinase; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
	MBM-55S 是一种有效的 Nek2 抑制剂，IC50 为 1 nM。 MBM-55S 抑制细胞周期停滞和凋亡，从而抑制癌细胞的增殖。 MBM-55S 表现出抗肿瘤作用。
T3465	Vesnarinone 维司力农,OPC-8212,Arkin,Piteranometozine	HIV Protease; PDE	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Vesnarinone (Arkin) 是一种喹啉酮衍生物，可抑制磷酸二酯酶III 活性，增加钙通量和减小钾通量。
T5618	AK-1	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	AK-1是一种特异性有效和细胞可渗透的SIRT2抑制剂，其IC50值为 12.5 μM。它可防止阿尔茨海默病模型中的海马神经退行性变并诱导结肠癌细胞中的细胞周期停滞。
T1272L	Cytarabine hydrochloride Ara-C hydrochloride,Cytosine Arabinoside hydrochloride	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Cytarabine hydrochloride (Ara-C hydrochloride) 是一种核苷类似物，可导致 S 期细胞周期停滞并抑制DNA 聚合酶。Cytarabine 抑制DNA 合成，IC50为 16 nM。Cytarabine hydrochloride 对HSV 具有抗病毒作用。
T64923	Sodium citrate Citrosodine,Natrocitral,柠檬酸钠	Others	Others
	Sodium citrate (Natrocitral) 是柠檬酸的钠盐。Sodium citrate 诱导G2/M 期和S 期细胞凋亡和细胞周期阻滞。Sodium citrate 通过降低抗氧化酶活性引起肝脏氧化损伤。

化合物

Cat.No: T11960

Target: GSK-3, MAPK, DYRK, Akt, Chk, Bcr-Abl, CDK, S6 Kinase, Aurora Kinase

Cat.No: T14066

Target: Apoptosis, GSK-3, Autophagy

Cat.No: T23133

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

Cat.No: T6207

Target: Apoptosis, Interleukin

Cat.No: T22461

Target: CDK

Cat.No: T15012

Synonym: EPC2407

Target: Microtubule Associated

S-trityl-L-Cysteine

Cat.No: T36816

Synonym: STLC

Target: Kinesin

Cat.No: T10460

Synonym: 巴他布林,T138067

Target: Apoptosis, Microtubule Associated

Pentamidine isethionate

Cat.No: T1654

Synonym: Pentamidine isethionate salt,Pentamidine diisethionate,喷他脒羟乙磺酸盐

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

Cat.No: T2641

Synonym: KRCA 0008,KRCA0008

Target: ACK, ALK

Cat.No: T4215

Synonym: 5-[[3-(三氟甲基)苯基]亚甲基]-2,4-噻唑烷二酮,SMI-4a

Target: Apoptosis, Pim

OTS514 hydrochloride

Cat.No: T4134

Synonym: OTS-514 hydrochloride,OTS514 hydrochloride(1338540-63-8(free base))

Target: Apoptosis, TOPK

Pentamidine dihydrochloride

Cat.No: T23132

Synonym: 喷他脒二盐酸盐,MP-601205 dihydrochloride

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

Cat.No: T2241

Synonym: MLN 8237,4-[[9-氯-7-(2-氟-6-甲氧基苯基)-5H-嘧啶并[5,4-D][2]苯并氮杂卓-2-基]氨基]-2-甲氧基苯甲酸

Target: Apoptosis, Aurora Kinase, Autophagy

CCT128930 hydrochloride

Cat.No: T6303L

Synonym: CCT128930 hydrochloride(885499-61-6 Free base)

Target: Apoptosis, Akt, PKA, mTOR, Autophagy

SKF-96365 hydrochloride

Cat.No: T2170

Synonym: 1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑,SKF96365

Target: Apoptosis, Potassium Channel, Calcium Channel, TRP/TRPV Channel, Autophagy

Cat.No: T6303

Target: Akt, PKA, S6 Kinase, Autophagy

Cat.No: T4134L

Synonym: OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514

Target: Apoptosis, TOPK

Cat.No: T10343

Synonym: N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: T9712

Synonym: PF-07104091

Target: CDK

Cat.No: T2425

Synonym: KPT-185,KPT 185

Target: CRM1

Triciribine phosphate

Cat.No: T19699

Synonym: TCN-P,VD 002,VQD-002

Target: Apoptosis, Akt

Cat.No: T34262

Target: Apoptosis

Flavopiridol hydrochloride

Cat.No: T2615

Synonym: Alvocidib Hydrochloride,NSC 649890,MDL 107826A,HL 275,FLAVOPIRIDOL HCL,NSC 649890 HCl

Target: HIV Protease, CDK, Autophagy

Cat.No: T10268

Target: Others

Cat.No: T17187

Target: Apoptosis, E1/E2/E3 Enzyme

Tubulin polymerization-IN-43

Cat.No: T77647

Target: Apoptosis, Microtubule Associated

Cat.No: T0975

Synonym: CB-1348,Chloroambucil,苯丁酸氮芥,WR-139013

Target: DNA Alkylator/Crosslinker, DNA Alkylation

Cat.No: T3485

Synonym: AT-2153,MM-159

Target: Others

4-Oxofenretinide

Cat.No: T4189

Synonym: 3-Keto fenretinide,4-氧代维甲酰酚胺

Target: cell cycle arrest

Cat.No: T77667

Target: Apoptosis, PI3K

Cat.No: T19831

Synonym: 草氨酸钠,oxamate sodium,Oxamic acid sodium salt,Aminooxoacetic acid sodium salt,SO

Target: Apoptosis, Dehydrogenase, CDK

Cat.No: T36898

Synonym: Sandranol,2-Ethyl-4-(2,2,3-trimethylcyclopent-3-en-yl)-but-2-en-1-ol

Target: Apoptosis

Cat.No: T11718

Synonym: JI-051

Target: Gamma-secretase

Cat.No: T3048

Synonym: c-Myc Inhibitor

Target: c-Myc, Autophagy

Cat.No: T73515

Target: Apoptosis, HDAC

Cat.No: T1844

Synonym: (E)-RN,KPT-330,KPT330,KPT 330

Target: Others, CRM1

Cat.No: T22646

Synonym: CFM-4,CFM4

Target: Apoptosis, APC

Cat.No: T24212

Synonym: XX65023,XX 650 23

Target: Apoptosis, Epigenetic Reader Domain

Tubulin inhibitor 32

Cat.No: T78701

Target: Apoptosis

Ceramides Mixture

Cat.No: T10760

Synonym: 神经酰胺混合物,神经酰胺

Target: Telomerase

Cat.No: T12040

Synonym: RAIN-32,DS-3032,DS3032b

Target: Mdm2, Others

Cat.No: T9703

Target: Epigenetic Reader Domain

Cat.No: T67741

Target: Others

Cat.No: T6970

Synonym: RK-33,RK 33

Target: COX

Cat.No: T11961

Target: GSK-3, MAPK, Akt, Bcr-Abl, CDK, S6 Kinase, Aurora Kinase

Cat.No: T3465

Synonym: 维司力农,OPC-8212,Arkin,Piteranometozine

Target: HIV Protease, PDE

Cat.No: T5618

Target: Sirtuin

Cytarabine hydrochloride

Cat.No: T1272L

Synonym: Ara-C hydrochloride,Cytosine Arabinoside hydrochloride

Target: DNA/RNA Synthesis

Cat.No: T64923

Synonym: Citrosodine,Natrocitral,柠檬酸钠

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1019	Beta-mangostin β-Mangostin,beta-倒捻子素	Apoptosis; Antibacterial; Parasite	Apoptosis; Microbiology/Virology
	Beta-mangostin (β-Mangostin) 是存在 Cratoxylum arborescens 中的一种氧杂蒽酮类天然产物，有抗癌和抗菌活性，对结核分枝杆菌的 MIC 值为 6.25 μg/mL。它在体外有抗疟活性，对恶性疟原虫的 IC50值为 3.00 μg/mL。
T2764	(S)-10-Hydroxycamptothecin 10-羟喜树碱,10-羟基喜树碱,10-Hydroxycamptothecin,10-HCPT	Apoptosis; Topoisomerase	Apoptosis; DNA Damage/DNA Repair
	(S)-10-Hydroxycamptothecin (10-HCPT) 是一种从喜树中分离的 DNA 拓扑异构酶 I 抑制剂。它显著诱导细胞凋亡，可研究肝癌、胃癌、结肠癌和白血病。
T3909	Pulsatilla saponin D 白头翁皂苷D,Hederacolchiside A,SB365	Apoptosis; Others	Apoptosis; Others
	Pulsatilla saponin D (Hederacolchiside A) 是从朝鲜白头翁根部分离得到的一种天然产物，具有抗癌活性。
T2S0886	Terrestrosin D	Apoptosis; Others	Apoptosis; Others
	Terrestrosin D 是从刺蒺藜中提取得到一种的甾体皂苷，可诱导细胞周期阻滞和癌细胞凋亡，具有抗血管生成的活性。
T6S2038	Ziyuglycoside II	Apoptosis; Antioxidant; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Ziyuglycoside II 是从地榆中提取的一种三萜皂苷，可诱导活性氧产生和凋亡，具有抗炎和抗癌作用。
TN1658	Ganoderenic acid D	Apoptosis; Others	Apoptosis; Others
	Ganoderenic acid D 是从灵芝提取物 (GLE) 的有效化合物中分离出来的天然产物。 Ganoderenic acid D 诱导细胞周期停滞和细胞凋亡并抑制癌细胞的增殖。
T2336	Vitamin K2 Menatetrenone,四烯甲萘醌	Endogenous Metabolite	Metabolism
	Vitamin K2 (Menatetrenone) 是内源性代谢产物的一种。
T1508	Decitabine Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA Methyltransferase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Decitabine (Deoxycytidine) 是脱氧胞苷类似物，一种 DNA 甲基转移酶抑制剂，具有口服活性。Decitabine 具有抗肿瘤活性和抗代谢活性。Decitabine 诱导细胞周期阻滞和凋亡。
T3774	Gracillin 山药,纤细薯蓣皂苷	cell cycle arrest	Cell Cycle/Checkpoint
	Gracillin 是一种甾体皂苷，从植物的根里提取得到，有抗肿瘤作用。
TN1244	3'-Demethylnobiletin	LDL; NF-κB; Integrin; Lipoxygenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Metabolism; NF-κB
	3'-Demethylnobiletin 是样一种存在于柑橘类水果中的多甲氧基黄酮类化合物，是一种 Nobiletin 的衍生物。N 其中 obiletin 能够调节 Src，FAK 和 STAT3 信号传导来抗肿瘤，并能够抑制肿瘤血管生成。
T2S0820	Karanjin 干华豆晶 4,水黄皮素	Apoptosis; AMPK	Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Karanjin 是干花豆中的主要活性呋喃黄酮醇成分，可通过细胞周期阻滞诱导癌细胞死亡，促进细胞凋亡，还通过提高AMPK 的方式诱导骨骼肌细胞 GLUT4 易位。
T6S0234	Toosendanin	Others	Others
	Toosendanin 是一种从杜鹃花果实皮中提取的三萜，具有杀虫和抗炎活性，可用于研究缓解疼痛。
T4S1540	Myrislignan	Apoptosis; NF-κB	Apoptosis; NF-κB
	Myrislignan 是一种木酚素，从Myristica fragransHoutt 分离得到，具有抗炎作用。它通过抑制NF-kB 信号通路的激活，减轻LPS 诱导的小鼠巨噬细胞炎症反应。
T1272	Cytarabine 阿糖胞苷,Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; HSV	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Cytarabine (Ara-C) 是一种核苷类似物，一种 DNA 合成抑制剂 (IC50=16 nM)。Cytarabine 可以抑制 DNA 聚合酶，诱导细胞周期阻滞、细胞自噬和凋亡。Cytarabine 具有抗肿瘤活性。
T3008	Lawsone methyl ether 2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone,2-甲氧基-1,4-萘并醌	Apoptosis; Antibacterial; Antifungal	Apoptosis; Microbiology/Virology
	Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) 是从凤仙花和Swertia calycina 中分离出的，有抗真菌和抗菌活性。
TN1620	Eriocalyxin B 毛萼乙素	Apoptosis; cAMP; NF-κB; STAT	Apoptosis; GPCR/G Protein; JAK/STAT signaling; NF-κB; Stem Cells
	Eriocalyxin B 是从中草药枇杷素中分离得到的一种二萜类天然产物，可诱导细胞凋亡，具有抗癌和抗炎作用。
TN1222	26-Deoxyactein 27-Deoxyactein,脱氧升麻烃,23-epi-26-Deoxyactein,27-脱氧升麻亭	NOS; CDK; NO Synthase	Cell Cycle/Checkpoint; Immunology/Inflammation
	23-epi-26-Deoxyactein (27-Deoxyactein) 是一种黑升麻中的主要成分，能够阻止 TCDD 诱导的成骨细胞的损伤。它对 AhR，CYP1A1 和 ERK 的水平升高具有抑制作用。
TN1804	Isosilybin A 异水飞蓟素 A,异水飞蓟宾A,水飞蓟素 B2	Apoptosis; Tyrosinase; PPAR; ABC	Apoptosis; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome
	Isosilybin A 是从水飞蓟中分离出来的一种黄酮木脂素，可抑制癌细胞增殖并诱导 G1 期停滞和凋亡，通过靶向 Akt-NF-κB-雄激素受体轴激活前列腺癌细胞的凋亡机制，具有抗前列腺癌活性。
T2220	2-Methoxyestradiol 2-甲氧雌二醇,二甲氧基雌二醇,NSC-659853,2-MeOE2,2-ME2	Apoptosis; Reactive Oxygen Species; Microtubule Associated; Endogenous Metabolite; HIF; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
	2-Methoxyestradiol (2-ME2) 是一种口服生物可利用的雌二醇代谢物，具有抗肿瘤活性。它通过减少内皮细胞增殖和诱导内皮细胞凋亡来抑制血管生成，也可破坏微管的稳定。它可诱导半胱天冬酶活化，导致细胞周期停滞在 G2 期、DNA 断裂和细胞凋亡。
T5S0527	Rhodojaponin III 闹羊花素 Ⅲ,闹羊花毒素III	Others	Others
	Rhodojaponin III 是二萜类化合物，提取于Rhododendron molle 叶子，具有抗炎作用。
T3386	Kaempferitrin Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷	cell cycle arrest; Glucokinase; IGF-1R	Cell Cycle/Checkpoint; Metabolism; Tyrosine Kinase/Adaptors
	Kaempferitrin (Lespenephryl) 是天然黄酮苷类化合物，具有缓解疼痛、抗糖尿病、消炎、抗肿瘤和化疗作用，可激活胰岛素信号传导。
T3S0081	Oxypeucedanin (+-)-Oxypeucedanin,氧化前胡素,Oxypeucadanin	Potassium Channel	Membrane transporter/Ion channel
	Oxypeucedanin ((+-)-Oxypeucedanin) 是呋喃香豆素衍生物，分离自Angelica dahurica。它是选择性开放通道阻滞剂，可抑制hKv1.5通道电流，IC50值为 76 nM。它延长心脏动作电位持续时间，是潜在的抗心律失常试剂。它通过抑制癌细胞迁移来诱导细胞凋亡。
T4S1615	Sanggenon C 桑根酮C,桑根酮 C,Sanggenone C	NF-κB	NF-κB
	Sanggenon C (Sanggenone C) 是一种从桑属的根皮中分离得到的黄烷酮 Diels-Alder 加合物化合物。它可抑制NF-κB 活性，抑制 RAW264.7 细胞中诱导型一氧化氮合酶的表达，以及肿瘤坏死因子-α 刺激的细胞粘附和血管细胞粘附分子-1 的表达。它具有抗氧化和抗炎作用，也有抑制胰脂肪酶作用。
T3426	Bacoside A	MMP; Others; TNF; Dopamine Receptor; NOS; ROS	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience; Others; Proteases/Proteasome
	Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidative stress by an increase in the concentration of antioxidant enzymes and sustain membrane integrity which leads to restoring the damage caused by tBHP. Bacoside A can able to inhibit the progression of Experimental Autoimmune Encephalomyelitis (EAE) may be by the inhibition of i...
T6S1917	Schisandrol B Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B	P450; Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Schisandrol B (Besigomsin) 是华中五味子的主要活性成分，具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生，也抑制 P-糖蛋白和CYP3A 的活性。
T2S2215	Crebanine	Apoptosis; Others; Akt	Apoptosis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling
	Crebanine 是来自于韦诺萨千金藤的一种生物碱，通过抑制 MAPKs 和 Akt 信号通路表现出抗炎活性，还具有抗心律失常的作用。它可诱导人类癌细胞的 G1阻滞和凋亡。
T37067	9-hydroxy Stearic Acid	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	9-hydroxy Stearic Acid 是一种羟基脂肪酸，是9-PAHSA 的活性代谢物。9-hydroxy Stearic Acid 是由9-PAHSA 通过肝脏和胰腺的羧基酯脂肪酶形成的。9-hydroxy Stearic Acid (5 μM)抑制HT-29结肠癌细胞裂解物中组蛋白去乙酰化酶1 (HDAC1)的表达。3 .当浓度为100 μM.1时，可抑制HT-29细胞的增殖，并诱导细胞周期阻滞于G0/ g1期。
T6S1315	Oroxylin A 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy	Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮，具有较强的抗癌作用。
T3824	Jaceosidin	Apoptosis; BCL; COX; UGT	Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
	Jaceosidin 是从毛莲蒿中得到的一种黄酮类天然产物，可激活Bax，下调 Mcl-1 和 c-FLIP 的表达，诱导癌细胞凋亡。它能够降低炎性因子水平，激活 NF-κB，抑制COX-2的表达，具有抗癌和抗炎作用。
TN1141	Isodeoxyelephantopin 异去氧苦地胆素,异去氧苦地胆苦素	NF-κB; Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Isodeoxyelephantopin 是从地胆草中分离得到的一种倍半萜烯内酯，能调节 LncRNA 的表达，有抗乳腺癌的作用。它可诱导活性氧的生成，抑制 NF-κB 的激活。
TN6511	Tessaric acid
	Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
TN5371	8-Hydroxy-ar-turmerone
	8-Hydroxy-ar-turmerone may exhibit antitumor activity against breast cancer cells via cell death and cell cycle arrest.
TN6547	Angustifoline 鲁冰花
	Angustifoline has activity against gram-positive bacteria. It inhibits human colon cancer cell growth by inducing autophagy along with mitochondrial-mediated apoptosis, suppression of cell invasion and migration and stimulating G2/M cell cycle arrest.
T27711	Kahweol Eicosanate J002075,J 002075,J-002075
	Kahweol Eicosanate is a semi-syntetic derivative of kahweol. Kahweol Eicosanate exhibits a wide variety of biological activities, including inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, inhibiting RANKL-induced osteoclast
TN4132	Germanicol
	Germanicol induces selective growth inhibitory effects in human colon HCT-116 and HT29 cancer cells through induction of apoptosis, cell cycle arrest and inhibition of cell migration. Germanicol may have anti-inflammatory effects .
T3930	Taraxerol acetate 醋酸蒲公英霜,Taraxeryl acetate	Phosphatase; HSV	Metabolism; Microbiology/Virology
	Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activity, could be attributed due to PTP
TN1728	Hellebrigenin	PARP; Akt; CDK	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Hellebrigenin exhibites moderate to strong activity against human HL-60, SF-295, MDA-MB-435, and HCT-8 cancer cell strains without hemolysis of mouse erythrocytes.
TN1617	Ergosta-4,6,8(14),22-tetraen-3-one	BCL; Caspase; p53	Apoptosis; Proteases/Proteasome
	Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of man
TN6591	Cannabisin B
	Cannabisin B possesses considerable antiproliferative activity and that it may be utilised as a promising chemopreventive agent against hepatoblastoma disease. It induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arre
T78479	Manool
	Manool为Salvia officinalis中的一种二萜，能在癌细胞中引发选择性细胞毒性，并导致癌细胞在细胞周期的G(2)/M期停滞。
T75569	Xerophilusin B
	Xerophilusin B 是一种从 Isodon xerophilus 中分离得到的抗癌剂，对食管鳞状细胞癌 (ESCC) 细胞系表现出抗增殖作用，可诱导 G2/M 细胞周期停滞，介导细胞凋亡 apoptosis。
T75698	Xylopine
	Xylopine 是一种具有细胞毒活性的阿朴啡生物碱，能诱导癌细胞氧化应激，从而引发 G2/M 细胞周期停滞及细胞凋亡(apoptosis)。
T75669	Odoroside A
	Odoroside A，一种自夹竹桃叶中提取的有效成分，具抗癌活性。它通过ROS/p53信号通路诱导细胞凋亡及细胞周期阻滞，进而引发肿瘤细胞死亡。
T70495	Scytonemin
	Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin , representing a novel Plk1 inhibitor, ...
T73681	Aspidin BB
	Aspidin BB 是一种间苯三酚衍生物，可从 Dryopteris championii 地上部分中分离得到。Aspidin BB 具有抗癌活性。Aspidin BB 在人卵巢 HO-8910 细胞中诱导细胞周期停滞和细胞凋亡 (apoptosis)。
TN4263	Isoangustone A	MMP; GSK-3; NF-κB; ROS; Akt; PI3K; CDK; JNK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoangustone A dampens mesangial sclerosis associated with inflammation in response to high glucose through hindering TGF-β and NF-ÎºB signaling. Isoangustone A also shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.
TN5264	Xanthoxyletin	TNF; NOS; ROS; COX; Antifection	Apoptosis; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory effect on iNOS protein expression at 10 microM, it also can inhibit the synthesis of nitric oxide and the protein expression of tumor necrosis factor-alpha and cyclooxygenase-2. Xanthoxyletin induces S phase arrest and apoptosis in human gastric adenocarcinoma SGC-7901 cells, the effects are associated with the DNA damage, apoptosis thro...
T75622	β-Apopicropodophyllin
	β-Apopicropodophyllin 是一种天然产物，可以从Hyptis wticillata 中分离得到。β-Apopicropodophyllin 通过诱导微管破坏、DNA 损伤、细胞周期停滞和 ER 应激来诱导细胞凋亡。β-Apopicropodophyllin 可用于癌症研究。
TN2344	Swainsonine Tridolgosir	Apoptosis; Others; Antibiotic	Apoptosis; Microbiology/Virology; Others
	Swainsonine (Tridolgosir) 是一种从黄芪中分离出来的一种生物碱，是一种强效和可逆的α-甘露糖苷酶抑制剂。Swainsonine 具有抗肿瘤活性，可诱导细胞凋亡和细胞周期停滞在 G2/M 期。
TN4168	Grifolin	Others	Others
	Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proliferation of oligodendrocyte precurs
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天然产物

Cat.No: TN1019

Synonym: β-Mangostin,beta-倒捻子素

Target: Apoptosis, Antibacterial, Parasite

(S)-10-Hydroxycamptothecin

Cat.No: T2764

Synonym: 10-羟喜树碱,10-羟基喜树碱,10-Hydroxycamptothecin,10-HCPT

Target: Apoptosis, Topoisomerase

Pulsatilla saponin D

Cat.No: T3909

Synonym: 白头翁皂苷D,Hederacolchiside A,SB365

Target: Apoptosis, Others

Cat.No: T2S0886

Target: Apoptosis, Others

Ziyuglycoside II

Cat.No: T6S2038

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Ganoderenic acid D

Cat.No: TN1658

Target: Apoptosis, Others

Cat.No: T2336

Synonym: Menatetrenone,四烯甲萘醌

Target: Endogenous Metabolite

Cat.No: T1508

Synonym: Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase

Cat.No: T3774

Synonym: 山药,纤细薯蓣皂苷

Target: cell cycle arrest

3'-Demethylnobiletin

Cat.No: TN1244

Target: LDL, NF-κB, Integrin, Lipoxygenase, DNA/RNA Synthesis

Cat.No: T2S0820

Synonym: 干华豆晶 4,水黄皮素

Target: Apoptosis, AMPK

Cat.No: T6S0234

Target: Others

Cat.No: T4S1540

Target: Apoptosis, NF-κB

Cat.No: T1272

Synonym: 阿糖胞苷,Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, HSV

Lawsone methyl ether

Cat.No: T3008

Synonym: 2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone,2-甲氧基-1,4-萘并醌

Target: Apoptosis, Antibacterial, Antifungal

Cat.No: TN1620

Synonym: 毛萼乙素

Target: Apoptosis, cAMP, NF-κB, STAT

Cat.No: TN1222

Synonym: 27-Deoxyactein,脱氧升麻烃,23-epi-26-Deoxyactein,27-脱氧升麻亭

Target: NOS, CDK, NO Synthase

Cat.No: TN1804

Synonym: 异水飞蓟素 A,异水飞蓟宾A,水飞蓟素 B2

Target: Apoptosis, Tyrosinase, PPAR, ABC

2-Methoxyestradiol

Cat.No: T2220

Synonym: 2-甲氧雌二醇,二甲氧基雌二醇,NSC-659853,2-MeOE2,2-ME2

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy

Rhodojaponin III

Cat.No: T5S0527

Synonym: 闹羊花素 Ⅲ,闹羊花毒素III

Target: Others

Cat.No: T3386

Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷

Target: cell cycle arrest, Glucokinase, IGF-1R

Cat.No: T3S0081

Synonym: (+-)-Oxypeucedanin,氧化前胡素,Oxypeucadanin

Target: Potassium Channel

Cat.No: T4S1615

Synonym: 桑根酮C,桑根酮 C,Sanggenone C

Target: NF-κB

Cat.No: T3426

Target: MMP, Others, TNF, Dopamine Receptor, NOS, ROS

Cat.No: T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Cat.No: T2S2215

Target: Apoptosis, Others, Akt

9-hydroxy Stearic Acid

Cat.No: T37067

Target: HDAC

Cat.No: T6S1315

Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Cat.No: T3824

Target: Apoptosis, BCL, COX, UGT

Isodeoxyelephantopin

Cat.No: TN1141

Synonym: 异去氧苦地胆素,异去氧苦地胆苦素

Target: NF-κB, Reactive Oxygen Species, Autophagy

Cat.No: TN6511

8-Hydroxy-ar-turmerone

Cat.No: TN5371

Cat.No: TN6547

Synonym: 鲁冰花

Kahweol Eicosanate

Cat.No: T27711

Synonym: J002075,J 002075,J-002075

Cat.No: TN4132

Taraxerol acetate

Cat.No: T3930

Synonym: 醋酸蒲公英霜,Taraxeryl acetate

Target: Phosphatase, HSV

Cat.No: TN1728

Target: PARP, Akt, CDK

Ergosta-4,6,8(14),22-tetraen-3-one

Cat.No: TN1617

Target: BCL, Caspase, p53

Cat.No: TN6591

Cat.No: T78479

Cat.No: T75569

Cat.No: T75698

Cat.No: T75669

Cat.No: T70495

Cat.No: T73681

Cat.No: TN4263

Target: MMP, GSK-3, NF-κB, ROS, Akt, PI3K, CDK, JNK

Cat.No: TN5264

Target: TNF, NOS, ROS, COX, Antifection

β-Apopicropodophyllin

Cat.No: T75622

Cat.No: TN2344

Synonym: Tridolgosir

Target: Apoptosis, Others, Antibiotic

Cat.No: TN4168

Target: Others

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